SEC inhibitor KL-1

SKU: orb1307748

Description

KL-1 is a potent and selective super elongation complex (SEC) inhibitor that disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 µM. This small molecule is a valuable chemical probe for studying transcriptional control in cancers and HIV latency reversal in both cellular and biochemical assays.

Research Area

Cell Biology

Key Properties

• CAS Number: 900308-84-1
• MW: 345.78
• Purity: >99.99% (May vary between batches)
• Formula: C₁₈H₁₆ClNO₄
• SMILES: COc1cccc(c1)C(=O)\C=C(/O)C(=O)Nc1cc(Cl)ccc1C
• Target: Apoptosis,Others
• Solubility: 10% DMSO+90% Corn Oil:2 mg/mL (5.78 mM);DMSO:41.67 mg/mL (120.51 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SEC inhibitor KL-1, SEC, SEC inhibitor KL 1, SEC inhibitor KL1, KL1, KL-1, KL 1

Compound Identifiers

PubChem CID

75186111