SD49-7

SKU: orb1685574

Description

SD49-7 is a potent and selective small molecule inhibitor of the KDM4 family of histone demethylases, exhibiting an IC50 of 0.19 µM. This compound is a valuable chemical probe for epigenetic research, enabling the study of histone methylation dynamics in both cellular and biochemical assays to investigate its roles in oncology and other disease fields.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 54009-54-0
• MW: 306.32
• Purity: 99.36% (May vary between batches)
• Formula: C₁₈H₁₄N₂O₃
• SMILES: C(=NNC(=O)C1=C(O)C=CC=C1)C=2C3=C(C=CC2O)C=CC=C3
• Target: DNA/RNA Synthesis,Histone Demethylase
• Solubility: DMSO:54.9 mg/mL (179.22 mM);Ethanol:4.5 mg/mL (14.69 mM)

Bioactivity

• Target IC50:
  KDM4:0.19 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

KDM4, HistoneDemethylase, Histone Demethylase, HNASH, SD49-7

Compound Identifiers

PubChem CID

598053