SCS

SKU: orb1305660

Description

SCS is a potent and selective small molecule inhibitor of α2β1γ1θ GABA(A) receptors, exhibiting a maximum inhibition of 56±5% with an IC50 of 32 nM. This compound is a valuable research tool for investigating the specific roles of this receptor subtype in neuropharmacology and neurological disorders using in vitro assays.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3232-36-8
• MW: 256.26
• Purity: 98.89%
• Formula: C₁₄H₁₂N₂O₃
• SMILES: Oc1ccccc1\C=N\NC(=O)c1ccccc1O
• Target: GABA Receptor
• Solubility: DMSO:50 mg/mL (195.11 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (3.9 mM)

Bioactivity

• Target IC50:
  α2β1γ1θ GABAA:32 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GABAA, GABAReceptor, GABA Receptor, SCS

Compound Identifiers

PubChem CID

135445765