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Scalaradial

SKU: orb3141612

Description

Scalaradial is an inhibitor of bee venom phospholipase A2 (PLA2) and TRPM ion channels (TRPM2) with IC50 values of 0.07 and 0.21 μM. It regulates ERK phosphorylation by inhibiting secretory PLA2 and Akt. Additionally, Scalaradial prevents the release of Arachidonic acid in mouse peritoneal macrophages induced by PMA.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number53527-28-9
MW428.60
FormulaC27H40O4
SMILESC[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)CCC3)[H])(C[C@H](OC(C)=O)[C@@]4(C)[C@]2(CC=C(C=O)[C@@H]4C=O)[H])[H]
TargetTRP/TRPV Channel,Phospholipase,Akt,ERK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information