Sarafotoxin S6a

SKU: orb1679234

Description

This compound is an endothelin receptor agonist, demonstrating potent vasoconstrictive activity in vitro with EC50 values of 7.5 nM in pig coronary artery and >150 nM in guinea pig aorta. It also exhibits nociceptive properties in vivo, making it a useful research tool for studying cardiovascular physiology and pain pathways.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Endothelin Receptor
• CAS Number: 126738-34-9
• MW: 2514.85
• Formula: C₁₀₅H₁₅₆N₂₈O₃₄S₅
• SMILES: C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@]4(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CSSC2)(CSSC4)[H])[H])[H])=O)CCC(N)=O)=O)CC(O)=O)=O)C(C)C)=O)[C@H](CC)C)=O)C(O)=O)C=5C=6C(NC5)=CC=CC6

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156595307