S100 Calcium Binding Protein A2 Antibody / S100A2

SKU: orb1824425

Description

S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. Cytoplasmic overexpression may also be of prognostic significance when observed in oral cancer patients, and the S100A2 has also been identified as significantly down regulated in gastric cancer.

Images & Validation

• Tested Applications: ELISA
• Dilution Range: ELISA (Order BSA-free format for coating)
• Reactivity: Human
• Application Notes:
  Optimal dilution of the S100 Calcium Binding Protein A2 antibody should be determined by the researcher.

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG2b
• Clone No.: rS100A2/6482
• Immunogen: Recombinant full-length human protein was used as the immunogen for the S100 Calcium Binding Protein A2 antibody.
• Purification: Protein A/G affinity
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

SDS-PAGE analysis of purified, BSA-free S100 Calcium Binding Protein A2 antibody (clone rS100A2/6482) as confirmation of integrity and purity.

Quick Database Links

UniProt

P29034