Rosolutamide

SKU: orb1737928

Description

Rosolutamide (ALZ-003) is an orally bioavailable curcumin analog that activates Nrf1/Nrf2 pathways. It has been investigated in preclinical models of neurodegenerative diseases, including Huntington's disease and spinocerebellar ataxia, for its ability to mitigate oxidative stress, reduce protein aggregation, and enhance mitochondrial function.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1039760-91-2
• MW: 464.55
• Purity: 99.36% (May vary between batches)
• Formula: C₂₈H₃₂O₆
• SMILES: C(CC1CCC1)(C(/C=C/C2=CC(OC)=C(OC)C=C2)=O)C(/C=C/C3=CC(OC)=C(OC)C=C3)=O
• Target: Nrf2,HSP,Androgen Receptor,Mitophagy
• Solubility: DMSO:27 mg/mL (58.12 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ASC-JM17, ASC-JM-17, ALZ-003, ALZ003, NSC5779, NSC-5779, Phenylthiourea, Phenylthiocarbamide, PTU, PTC

Compound Identifiers

PubChem CID

25183127