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Catalog Number | orb1688189 |
---|---|
Category | Small Molecules |
Description | Rosiglitazone potassium |
Purity | 98.00% |
MW | 395.52 |
Biological Activity | Rosiglitazone (BRL 49653) potassium is a potent and selective PPARγ agonist (EC 50: 60 nM, Kd: 40 nM), administered orally. It also serves as an activator of TRPC5 (EC 50: 30 μM) and an inhibitor of TRPM3. This compound, widely used in research, has shown promise in investigating obesity, diabetes, senescence, and ovarian cancer [1] [2] [4] [7]. |
CAS Number | 316371-84-3 |
Formula | C18H18KN3O3S |
SMILES | [K+].CN(CCOc1ccc(CC2SC(=O)[N-]C2=O)cc1)c1ccccn1 |
Storage | -20°C |
Note | For research use only |