RO-5328673

SKU: orb1738480

Description

RO-5328673 is a high-affinity dual NK2/NK3 receptor antagonist. It exhibits insurmountable antagonism in vitro and demonstrates robust in vivo efficacy, such as reversing senktide-induced locomotor activity in gerbils, making it a valuable research tool for studying neurokinin receptor function in both cellular and animal models.

Key Properties

• CAS Number: 1310817-94-7
• MW: 576.49
• Formula: C₂₉H₃₂Cl₂FN₃O₄
• SMILES: N(C(OC1=CC=C(F)C=C1)=O)(C)[C@H]2[C@@H](CN(C(=O)C3CCN(C(=O)C4(C)CC4)CC3)C2)C5=CC(Cl)=C(Cl)C=C5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53244787