Rizatriptan-d6 benzoate salt

• Catalog Number: orb1738269
• Category: Small Molecules
• Description: Rizatriptan-d6 benzoate salt
• CAS Number: 1216984-85-8
• Purity: 0.98
• MW: 397.5116
• SMILES: OC(=O)c1ccccc1.[2H]C([2H])([2H])N(CCc1c[nH]c2ccc(Cn3cncn3)cc12)C([2H])([2H])[2H]
• Formula: C₂₂H₁₉D₆N₅O₂
• Biological Activity: Rizatriptan-d6 is intended for use as an internal standard for the quantification of rizatriptan by GC- or LC-MS. Rizatriptan is an agonist of the serotonin receptor subtypes 5-HT1B and 5-HT1D. It is selective for 5-HT1B and 5-HT1D receptors over 5-HT1A receptors. Rizatriptan induces vasoconstriction in isolated human middle meningeal arteries. In vivo, rizatriptan reduces head grooming, the number of oculotemporal strokes, eye blinking, and one-eye closures in a Cacna1a mutant transgenic mouse model of migraine. Formulations containing rizatriptan have been used in the treatment of migraine.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.