Riddelline

SKU: orb1984167

Description

Riddelline is a genotoxic pyrrolizidine alkaloid used in research to study DNA damage response. It potently induces unscheduled DNA synthesis and increases S-phase synthesis in vitro, notably in rat liver models, making it a tool for investigating hepatotoxicity and chemical carcinogenesis mechanisms.

Research Area

Cardiovascular Research, Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 23246-96-0
• MW: 349.38
• Formula: C₁₈H₂₃NO₆
• SMILES: O=C/1O[C@]2([C@]3(C(COC(=O)[C@](CO)(O)C(=C)C\C1=C\C)=CCN3CC2)[H])[H]
• Target: VEGFR|||DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5281744