Ribociclib-d8

SKU: orb3138896

Description

Ribociclib-d8 is the deuterated form of Ribociclib, also known as LEE011, which acts as a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM. Its activity against the cyclin B/CDK1 complex is over 1000 times weaker.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2167898-24-8
• MW: 442.59
• Formula: C₂₃H₃₀N₈O
• SMILES: C(N(C)C)(=O)C=1N(C=2C(C1)=CN=C(NC3=CC=C(C=N3)N4C(C(NC(C4([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])N2)C5CCCC5
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CDK