Rezafungin acetate

SKU: orb1708667

Description

Rezafungin acetate is an echinocandin antifungal agent that inhibits 1,3-β-D-glucan synthase. It is used in research models of invasive candidiasis and aspergillosis, particularly for studying therapeutic interventions in immunocompromised hosts such as transplant recipients.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 1631754-41-0
• MW: 1285.44
• Purity: 99.76% (May vary between batches)
• Formula: C₆₅H₈₈N₈O₁₉
• SMILES: C(C)([O-])=O.O=C1N2[C@](C(=O)N[C@H](OCC[N+](C)(C)C)[C@H](O)C[C@H](NC(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CC=C(OCCCCC)C=C5)C(=O)N[C@@]([C@@H](C)O)(C(=O)N6[C@](C(=O)N[C@@]([C@@H]([C@@H](O)C7=CC=C(O)C=C7)O)(C(=O)N[C@]1([C@@H](C)O)[H])[H])(C[C@@H](O)C6)[H])[H])([C@@H](O)[C@@H](C)C2)[H]
• Target: Antifungal
• Solubility: DMSO:200 mg/mL (155.59 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (3.89 mM)

Bioactivity

• In Vivo:
  Rezafungin acetate (1 mg/kg; intraperitoneal injection once daily for 6 days) demonstrated favorable in vivo prophylaxis against Pneumocystis carinii infection in a mouse model of infection.

Storage & Handling

• Storage: store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Biafungin acetate, CD 101 acetate, CD-101 Acetate, CD101 acetate, SP3025 acetate, SP-3025 acetate, SP 3025 Acetate

Compound Identifiers

PubChem CID

78318118