Renin FRET Substrate I

SKU: orb1984771

Description

Renin FRET Substrate I is a fluorogenic peptide designed to mimic the native cleavage sequence of human angiotensinogen, serving as a specific substrate for human renin. It is widely used in high-throughput screening and biochemical assays to study renin activity and inhibitor efficacy in vitro.

Research Area

Metabolism Research

Key Properties

• Target: RAAS
• CAS Number: 142988-22-5
• MW: 1798.15
• Formula: C₉₀H₁₂₀N₂₂O₁₆S
• SMILES: CC[C@H](C)[C@H](NC(=O)CCCNC(=O)c1ccc(cc1)N=Nc1ccc(cc1)N(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCNc1cccc2c(cccc12)S(O)(=O)=O |w:20.20,@@:81|

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165365498