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rel-A-395 hydrochloride

SKU: orb3136345

Description

rel-A-395 hydrochloride is the relative configuration of A-395 hydrochloride. A-395 is an antagonist of protein-protein interactions within the polycomb repressive complex 2 (PRC2). It inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 value of 18 nM.

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Key Properties

CAS Number2747996-65-0
MW523.11
FormulaC26H36ClFN4O2S
SMILESFC1=C2C(CCC2=CC=C1)N3C[C@@H]([C@@H](N(C)C)C3)C4=CC=C(C=C4)N5CCN(S(C)(=O)=O)CC5.Cl
TargetHistone Methyltransferase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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rel-A-395 hydrochloride (orb3136345)

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