Regaloside A

SKU: orb1680261

Description

Regaloside A, a phenylpropanoid isolated from Convallaria majalis, exhibits antioxidant activity by scavenging DPPH free radicals at 160 ppm. This small molecule has demonstrated anti-inflammatory and antidepressant properties in preliminary research, making it a compound of interest for neurobiological and pharmacological studies.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 114420-66-5
• MW: 400.38
• Purity: 99.91%
• Formula: C₁₈H₂₄O₁₀
• SMILES: O(C[C@@H](COC(/C=C/C1=CC=C(O)C=C1)=O)O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O
• Target: NF-κB,Others,NO Synthase
• Solubility: DMSO:45 mg/mL (112.39 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5 mM)

Bioactivity

• In Vitro:
  Regaloside A (50 μg/mL; 2 h) followed by LPS treatment (1 μg/mL; 15 min) in RAW 264.7 cells inhibits iNOS expression to 70.3% and reduces COX-2 expression to 131.6%, also lowering the p-p65/p-65 ratio to 40.7; additionally, Regaloside A (50 μg/mL; 2 h) in HASMCs exposed to TNF-α (10 ng/mL; 12 h) reduces VCAM-1 expression to 48.6%.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Regaloside A

Compound Identifiers

PubChem CID

15589787