Rapamycin-d3

SKU: orb1990412

Description

Rapamycin-d3 is a deuterated form of the potent mTOR inhibitor Rapamycin, which exhibits an IC50 of 0.1 nM in HEK293 cells. This labeled compound is widely used as a critical research tool for studying mTOR signaling pathways in both cellular and animal models of aging, cancer, and metabolic diseases.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 392711-19-2
• MW: 917.19
• Formula: C₅₁H₇₉NO₁₃
• SMILES: [2H]C([2H])([2H])O[C@H]1C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@@H](CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C1/C)[C@H](C)C[C@@H]1CC[C@@H](O)[C@@H](C1)OC
• Target: FKBP,Autophagy,mTOR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

45040343