Rachelmycin

SKU: orb1690332

Description

Rachelmycin (CC-1065) is a potent antitumor antibiotic from Streptomyces zelensis that binds the DNA minor groove, forming covalent N3-adenine adducts. Its exceptional cytotoxicity has driven extensive research into its mechanisms and potential therapeutic applications in both in vitro and in vivo cancer models.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 69866-21-3
• MW: 703.712
• Formula: C₃₇H₃₃N₇O₈
• SMILES: [H][C@]12C[C@@]11C(=CC(=O)c3[nH]cc(C)c13)N(C2)C(=O)c1cc2c3CCN(C(=O)c4cc5c6CCN(C(N)=O)c6c(O)c(OC)c5[nH]4)c3c(O)c(OC)c2[nH]1 |c:5|
• Target: DNA/RNA Synthesis,Others,Antibiotic

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9939943