Quercetin-3-O-glucose-6''-acetate

SKU: orb1297224

Description

6"-O-Acetylisoquercitrin (Quercetin-3-O-glucose-6''-acetate) is a bioactive flavonoid derivative that functions as a NADPH oxidase inhibitor, exhibiting antioxidant properties. It is utilized in research areas such as oxidative stress, inflammation, and cardiovascular studies, with applications in both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 54542-51-7
• MW: 506.41
• Purity: 97.48%
• Formula: C₂₃H₂₂O₁₃
• SMILES: O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC(O)=C(O)C=C3)[C@@H]4O[C@H](COC(C)=O)[C@@H](O)[C@H](O)[C@H]4O
• Target: NADPH,NADPH-oxidase,ROS
• Solubility: DMSO:100 mg/mL (197.47 mM)

Bioactivity

• In Vitro:
  The mulberry leaf contains 4 flavonols in the following order: quercetin-3-β-D-glucose (QT-G) > quercetin-3-O-glucose-6'-acetate (QT-GA) > rutin (RT) > quercetin (QT). In the oxygen radical absorbance capacity (ORAC) assay, QT had the highest peroxyl radical-scavenging capacity and a similar hydroxyl radical-scavenging capacity as its glycosides (QT-G, QT-GA, and RT).

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ROS, Quercetin 3 O glucose 6'' acetate, Quercetin-3-O-glucose-6''-acetate, Quercetin3Oglucose6''acetate, NADPH oxidase, NADPHoxidase, NADPH-oxidase, 6"-O-Acetylisoquercitrin

Compound Identifiers

PubChem CID

10006384