PZ-1922

SKU: orb1943429

Description

PZ-1922 is a brain-penetrant small molecule with high-affinity dual antagonism of 5-HT6 and 5-HT3 receptors (Ki = 17 nM and 0.45 nM) and reversible MAO-B inhibition (pIC50 8.93). It has demonstrated efficacy in rodent models, reversing scopolamine-induced deficits in the NOR test and Aβ-induced impairment in the T-maze test, supporting research in neuropsychiatric and neurodegenerative disorders.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: Monoamine Oxidase,5-HT Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Monoamine Oxidase,5-HT Receptor