PROTAC-O4I2

• Catalog Number: orb1983144
• Category: Small Molecules
• Description: PROTAC-O4I2
• CAS Number: 2785323-62-6
• Purity: 96.31%
• MW: 609.1
• SMILES: O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCCCNC(=O)C=4N=C(NC5=CC=C(Cl)C=C5)SC4
• Formula: C₂₉H₂₉ClN₆O₅S
• Biological Activity: PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 μM. PROTAC-O4I2 induced apoptosis in K562 WT cells.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.