PROTAC EZH2 Degrader-1

SKU: orb1982793

Description

PROTAC EZH2 Degrader-1 (Compound 150d) is a potent, nanomolar-range degrader (IC50 = 2.7 nM) of the oncogenic histone methyltransferase EZH2. This chemical probe is a valuable tool for investigating EZH2 function and therapeutic potential in both cellular and in vivo cancer research models.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2641601-67-2
• MW: 942.15
• Formula: C₅₄H₆₇N₇O₈
• SMILES: O=C(NCC=1C(=O)NC(=CC1C)C)C2=CC(=CC(=C2C)N(CC)C3CCOCC3)C4=CC=C(C=C4)CN5CCN(CC5)CCCCCCCOC6=CC=CC=7C(=O)N(C(=O)C67)C8C(=O)NC(=O)CC8
• Target: PROTACs,Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156351362