PROTAC ER Degrader-4

SKU: orb1989663

Description

PROTAC ER Degrader-4 is a potent and selective proteolysis-targeting chimera (PROTAC) that induces degradation of the estrogen receptor (ER) with an IC50 of 0.8 nM. It is a valuable chemical tool for investigating ER biology and targeted protein degradation in both cellular and in vivo models of hormone-dependent cancers.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2361114-15-8
• MW: 1005.2
• Formula: C₅₃H₆₇F₃N₆O₈S
• SMILES: C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)COCCOCCOCCOc1cc(F)c([C@H]2N(CC(C)(C)F)[C@H](C)Cc3c2[nH]c2ccccc32)c(F)c1)C(C)(C)C)c1ccc(cc1)-c1scnc1C
• Target: PROTACs,Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138693144