PROTAC EGFR degrader 3

SKU: orb1983017

Description

PROTAC EGFR Degrader 3 is a potent and selective compound that effectively degrades mutant EGFR in cellular models such as H1975 and HCC827 cells. Its mechanism involves lysosomal pathways, making it a valuable chemical probe for studying targeted protein degradation in oncology research, both in vitro and in vivo.

Research Area

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2768472-28-0
• MW: 1092.4
• Formula: C₆₀H₇₇N₁₃O₅S
• SMILES: C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCCCN1CCN(CC1)c1ccc(Nc2ncc3nc(Nc4ccccc4)n([C@H]4CCCN(C4)C(=O)C=C)c3n2)cc1)C(C)(C)C)c1ccc(cc1)-c1scnc1C
• Target: EGFR,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162513220