PROTAC BTK Degrader-11

SKU: orb2802225

Description

PROTAC BTK Degrader-11 is a potent, small molecule PROTAC that induces degradation of Bruton's tyrosine kinase (BTK) with a DC50 of 1.7 nM. It is a valuable chemical tool for investigating BTK-dependent signaling in oncology research, applicable in both cellular and in vivo studies of B-cell malignancies.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2736508-94-2
• MW: 850.02
• Formula: C₄₈H₅₅N₁₁O₄
• SMILES: CC=1C=C(C2=C3C(NC(=C3)C=4C=CC(=NC4)N5CCN(CC6CCN(CC6)C7=CC=C(C=C7)C8C(=O)NC(=O)CC8)CC5)=NC=N2)C=CC1[C@H](NC(=O)C9=NC(C(C)(C)C)=NO9)C
• Target: PROTACs,BTK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166522043