PROTAC BRD4 degrader for PAC-1

SKU: orb1987808

Description

This PROTAC molecule is a chimeric degrader that selectively targets BRD4 for proteasomal degradation via a disulfide-containing linker. It is a valuable chemical tool for investigating BET protein function and targeted protein degradation in both cellular and in vivo research contexts.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 1306.58
• Formula: C₆₂H₇₇F₂N₉O₁₂S₄
• SMILES: O=C(C1=C(CS(=O)(C)=O)C=C(C(N(C2=NC=C(F)C=C2F)C3)=C1)C4=CN(C)C(C5=C4C3=CN5)=O)NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N6[C@H](C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)C[C@@H](OC(OCC(C)(C)SS(C)(=O)=O)=O)C6)=O)=O
• Target: PROTAC-Linker Conjugates for PAC,PROTAC-Linker Conjugates for PAC,PROTAC-Linker Conjugates for PAC,PROTAC-Linker Conjugates for PAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145712388