Propargyl-PEG4-acid

SKU: orb1909293

Description

Propargyl-PEG4-acid is a polyethylene glycol (PEG) linker utilized in constructing PROTAC molecules, such as BTK-targeting degraders derived from Ibrutinib. For instance, a related PROTAC 3 degrades Bruton's Tyrosine Kinase (BTK) with a DC50 of 200 nM in THP-1 cell-based assays, demonstrating its application in targeted protein degradation research.

Research Area

Pharmacology & Drug Discovery

Images & Validation

−

Key Properties

−

CAS Number	1415800-32-6
MW	260.28
Formula	C₁₂H₂₀O₆
SMILES	C(OCCOCCOCC#C)COCCC(O)=O
Target	PROTAC Linker,Others

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

77078488 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols