PPADS

SKU: orb2664424

Description

PPADS is a potent, competitive P2X1 and P2X3 receptor antagonist (IC50 68 nM and 214 nM, respectively) and a reversible NAADP receptor blocker. This ATP analog is used in research to study purinergic signaling, demonstrating efficacy in reducing hyperalgesia and modulating inflammatory pathways like NO/NOS and IL-1β in both in vitro and in vivo models.

Key Properties

• CAS Number: 149017-66-3
• MW: 511.38
• Formula: C₁₄H₁₄N₃O₁₂PS₂
• SMILES: O=CC1=C(O)C(=NC(N=NC2=CC=C(C=C2S(=O)(=O)O)S(=O)(=O)O)=C1COP(=O)(O)O)C

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

4881