Pomalidomide-PEG6-NH2 hydrochloride

SKU: orb1984584

Description

Pomalidomide-PEG6-NH2 hydrochloride is a key building block for constructing PROTAC degraders, linking the cereblon-targeting ligand pomalidomide to a warhead via a flexible PEG spacer. It is widely utilized in both in vitro and in vivo research for the targeted protein degradation of various disease-relevant targets.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2341841-01-6
• MW: 574.02
• Purity: 97.18% (May vary between batches)
• Formula: C₂₅H₃₆ClN₃O₁₀
• SMILES: Cl.O=C1C=2C=CC=C(OCCOCCOCCOCCOCCOCCN)C2C(=O)N1C3C(=O)NC(=O)CC3
• Target: E3 Ligase Ligand-Linker Conjugates
• Solubility: DMSO:110 mg/mL (191.63 mM)

Storage & Handling

• Storage: keep away from moisture,keep away from direct sunlight | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Pomalidomide PEG6 NH2 hydrochloride, PomalidomidePEG6NH2 hydrochloride, Pomalidomide-PEG-6-NH2 hydrochloride, Pomalidomide-PEG6-NH2 Hydrochloride, Pomalidomide-PEG6-NH2 hydrochloride

Compound Identifiers

PubChem CID

138991801