Pomalidomide-PEG2-NH2 hydrochloride

SKU: orb1303329

Description

This compound is a PROTAC linker-conjugate featuring a pomalidomide-derived CRBN E3 ligase ligand connected via a PEG2 spacer. It serves as a key component for constructing proteolysis-targeting chimeras (PROTACs) used in chemical biology and drug discovery research to induce targeted protein degradation in both cellular and in vivo studies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: E3 Ligase Ligand-Linker Conjugates,Others
• Molecular Weight: 454.86
• Purity: 97.95%
• Formula: C₁₉H₂₃ClN₄O₇
• SMILES: Cl.NCCOCCOCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PomalidomidePEG2NH2 hydrochloride, Pomalidomide-PEG-2-NH2 hydrochloride, Pomalidomide-PEG2-NH2 Hydrochloride, Pomalidomide PEG2 NH2 hydrochloride

Compound Identifiers

PubChem CID

139035194