Pomalidomide-benzyl-piperazine hydrochloride

SKU: orb2813968

Description

This bifunctional molecule serves as a key building block for constructing PROTACs and targeted protein degraders. It incorporates a CRBN-binding pomalidomide moiety, a stable benzyl-piperazine linker, and a reactive amine for conjugating to target ligands, enabling research into protein degradation in both cellular and in vivo models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 511.96
• Formula: C₂₅H₂₆ClN₅O₅
• SMILES: O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)C4=CC=C(CN5CCNCC5)C=C4.[H]Cl
• Target: Ligands for Target Protein for PROTAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171329204