Pomalidomide 4'-PEG3-azide

• Catalog Number: orb2279187
• Category: Small Molecules
• Description: Pomalidomide 4'-PEG3-azide is a chemically synthesized E3 ligase ligand-linker conjugate that incorporates the cereblon ligand derived from Pomalidomide, along with a linker. This compound is utilized in the synthesis of iRucaparib-TP3 (Compound 3), an effective PARP1 degrader developed through the PROTAC strategy and derived from Rucaparib.
• CAS Number: 2271036-46-3
• Purity: 98.72%
• MW: 474.47
• SMILES: [N-]=[N+]=NCCOCCOCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
• Formula: C₂₁H₂₆N₆O₇
• Biological Activity: Pomalidomide 4'-PEG3-azide is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker conjugate that incorporates the cereblon ligand derived from Pomalidomide, along with a linker. This compound, Pomalidomide 4'-PEG3-azide, is utilized in the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3, developed through the PROTAC strategy, is an effective degrader of PARP1, derived from Rucaparib.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.