PKR-IN-C51

SKU: orb1702934

Description

PKR-IN-C51 is a dose-dependent, ATP-competitive inhibitor of the interferon-induced kinase PKR, with a Ki of 3.4 µM. It effectively blocks PKR autophosphorylation and activation in cellular models like macrophages, making it a valuable research tool for studying PKR's role in viral infection, inflammation, and cellular stress responses in vitro.

Research Area

Cell Biology, Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 1314594-23-4
• MW: 367.45
• Purity: 98.94% (May vary between batches)
• Formula: C₂₃H₂₁N₅
• SMILES: N1=CC=C(N=C1NCCC2=CNC=3C=CC=CC32)C=4C=5C=CC=CC5NC4C
• Target: Serine/threonin kinase,Serine Protease
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.89 mM);DMSO:100 mg/mL (272.15 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PKRINC 51, PKRINC51, PKR-IN-C51, PKR-IN-C-51, PKRINC-51, PKR-inhibitor-C51, PKR IN C51, PKR inhibitor C51

Compound Identifiers

PubChem CID

53307873