Phosphoramide mustard

SKU: orb1692030

Description

Phosphoramide mustard

Research Area

Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 10159-53-2
• MW: 221.02
• Purity: 93.00% (May vary between batches)
• Formula: C₄H₁₁Cl₂N₂O₂P
• SMILES: O=P(O)(N)N(CCCl)CCCl
• Target: DNA Alkylator/Crosslinker,Drug Metabolite,DNA Alkylation

Bioactivity

• In Vivo:
  In the rat model of subcutaneously implanted Walker 256 carcinosarcoma tumors, Phosphoramide mustard (12 mg/kg; intraperitoneal injection, once daily, for 5 consecutive days) inhibited subcutaneous tumor growth by 50%.
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• In Vitro:
  In SIGCs cell lines, Phosphoramide mustard (0.5 μM, 1 μM, 3 μM, 6 μM; 48 hours) reduced cell viability.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Drug Metabolite, DNA alkylator, DNA Alkylation, DrugMetabolite, DNAAlkylation, Phosphoramide mustard

Compound Identifiers

PubChem CID

96356