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Catalog Number | orb1730673 |
---|---|
Category | Antibodies |
Description | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | ICC, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | A synthesized peptide derived from human Phospho-B Raf (T401) |
Dilution range | IP: 1/20; WB: 1/500-1/1000; ICC: 1/50-1/200 |
Conjugation | Unconjugated |
MW | Calculated MW: 84 kDa; Observed MW: 84 kDa |
Entrez | 673 |
UniProt ID | P15056 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Alternative names | BRAF; BRAF1; RAFB1; Serine/threonine-protein kinas Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ICC, IP, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
IP, WB | |
Human, Mouse, Rat | |
Rabbit | |
Monoclonal | |
Unconjugated |
IP, WB | |
Human, Mouse, Rat | |
Rabbit | |
Monoclonal | |
Unconjugated |
WB | |
Human, Mouse, Rat | |
Rabbit | |
Recombinant | |
Unconjugated |
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