PF3274167

SKU: orb1304299

Description

PF3274167 (Cligosiban) is a potent, selective, and high-affinity nonpeptide antagonist of the oxytocin receptor. It is a valuable research tool for investigating oxytocin-mediated pathways in both in vitro and in vivo models, particularly within neuropsychiatric and reproductive research fields.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 900510-03-4
• MW: 419.84
• Purity: 99.88%
• Formula: C₁₉H₁₉ClFN₅O₃
• SMILES: C(OC)C=1N(C(=NN1)N2CC(OC3=C(Cl)C=C(F)C=C3)C2)C=4C=CC(OC)=NC4
• Target: Oxytocin Receptor,OX Receptor
• Solubility: DMSO:55 mg/mL (131 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (5.95 mM)

Bioactivity

• Target IC50:
  OTR:9.5 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

OXTR, OXReceptor, PF 3274167, PF3274167, PF-3274167, Cligosiban, OX Receptor

Compound Identifiers

PubChem CID

11683187