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PF-04745637

SKU: orb1685709

Description

PF-04745637

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1917294-46-2
MW509
Purity98.88%
FormulaC27H32ClF3N2O2
SMILESOC1(CCN(CC1)C(CNC(=O)C1(CCCC1)c1ccc(Cl)cc1)Cc1ccccc1)C(F)(F)F
TargetTRP/TRPV Channel
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.93 mM);DMSO:60 mg/mL (117.88 mM)

Bioactivity

Target IC50
TRPA1:17 nM
In Vivo
PF-04745637 (topically applied; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, inflammatory, bowel, disease, Transient receptor potential channels, TRP Channel, TRPV Channel, TRPVChannel, TRPChannel, TRPA1, respiratory, skin, PF4745637, PF-4745637, PF04745637, PF-04745637, PF 04745637, PF 4745637

Similar Products

  • PF-04745637 [orb1940854]

    >98% (HPLC)

    1917294-46-2

    509.01

    C27H32ClF3N2O2

    25 mg, 50 mg, 10 mg, 1 g, 100 mg, 500 mg, 5 mg
Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

PF-04745637 (orb1685709)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 190.00
1 ml x 10 mM (in DMSO)
$ 210.00
10 mg
$ 250.00
25 mg
$ 390.00
50 mg
$ 540.00
100 mg
$ 730.00
200 mg
$ 970.00
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