PF-03814735

SKU: orb3137125

Description

PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.

Key Properties

• CAS Number: 942487-16-3
• MW: 474.48
• Formula: C₂₃H₂₅F₃N₆O₂
• SMILES: CC(=O)NCC(=O)N1[C@H]2CC[C@@H]1c1cc(Nc3ncc(c(NC4CCC4)n3)C(F)(F)F)ccc21
• Target: FLT,Trk receptor,FAK,Aurora Kinase,VEGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

FLT,Trk receptor,FAK,Aurora Kinase,VEGFR