PF-00337210

SKU: orb1740934

Description

PF-00337210 is an orally bioavailable, ATP-competitive inhibitor selectively targeting VEGFR2 tyrosine kinase. Its inhibition of VEGFR2 phosphorylation disrupts tumor angiogenesis, as demonstrated in in vitro endothelial cell assays and in vivo xenograft models, supporting its investigation as an antineoplastic agent.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 854514-88-8
• MW: 461.51
• Formula: C₂₆H₂₇N₃O₅
• SMILES: C(NC)(=O)C=1C=2C(=CC(OC=3C4=C(C=C(OCCN5CCOCC5)C=C4)N=CC3)=CC2)OC1C
• Target: VEGFR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11236560