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PERK-IN-4

SKU: orb2900953

Description

PERK-IN-4 is a potent and selective PERK (protein kinase R (PKR)-like endoplasmic reticulum kinase) inhibitor with an IC 50 of 0.3 nM. PERK is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states.

Images & Validation

Key Properties

CAS Number1337531-89-1
MW469.43
Purity>98% (HPLC)
FormulaC24H19F4N5O
SMILESCn1cc(-c2ccc3N(CCc3c2)C(=O)Cc2cc(F)cc(c2)C(F)(F)F)c2c(N)ncnc12
TargetPERK
SolubilityIn Vitro: DMSO : 20.83 mg/mL (44.37 mM; Ultrasonic )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • PERK-IN-4 [orb1691811]

    99.49% (May vary between batches)

    1337531-89-1

    469.43

    C24H19F4N5O

    5 mg, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg
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Protocol Information

PERK-IN-4 (orb2900953)

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Available Sizes

Select a size below

500 mg
2 mg
$ 140.00
5 mg
$ 200.00
10 mg
$ 300.00
25 mg
$ 510.00
50 mg
$ 740.00
100 mg
$ 1,000.00