pep2-AVKI

SKU: orb1679409

Description

Pep2-AVKI is a selective peptide inhibitor that disrupts the GluA2-PICK1 PDZ domain interaction without affecting GluA2 binding to GRIP/ABP or altering AMPA currents and LTD. It is a valuable tool for studying AMPA receptor trafficking, synaptic plasticity, and roles in neurological disorders in both in vitro and in vivo models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: iGluR
• CAS Number: 1315378-69-8
• MW: 1268.47
• Formula: C₆₀H₉₃N₁₃O₁₇
• SMILES: [C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CC(N)=O)=O)[C@@H](C)C)=O)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CCCCN)=O)C(C)C)=O)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90479810