Pencitabine

SKU: orb1688198

Description

Pencitabine is an orally active small molecule antimetabolite that disrupts DNA synthesis via dual mechanisms: inhibiting key nucleotide-metabolizing enzymes and acting as a chain terminator through direct misincorporation into DNA. It is used in cancer research, particularly in studies of leukemia and solid tumors, for both in vitro cytotoxicity assays and in vivo xenograft model experiments.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 2249843-29-4
• MW: 395.33
• Formula: C₁₅H₂₀F₃N₃O₆
• SMILES: FC1(F)[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(OCCCCC)=O)C(F)=C2
• Target: Others,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

142464466