PEN-866

SKU: orb1738903

Description

PEN-866 is a novel small molecule conjugate designed for NSCLC research, combining an HSP90 inhibitor with the topoisomerase I inhibitor SN-38 via an esterase-cleavable linker. It has demonstrated potential in suppressing early-stage tumor growth in both in vitro and in vivo preclinical models.

Key Properties

• CAS Number: 1472614-83-7
• MW: 879.95
• Formula: C₄₉H₄₉N₇O₉
• SMILES: C(C)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC(OC(=O)N6CCC(CCN7C=8C(C=C7)=CC(=CC8)N9C(=NNC9=O)C%10=CC(C(C)C)=C(O)C=C%10O)CC6)=CC5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135564925