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PEAQX

SKU: orb1303092

Description

PEAQX (NVP-AAM077) is a potent, orally bioavailable NMDA receptor antagonist with selectivity for GluN1/GluN2A subunits (IC50: 270 nM) over GluN1/GluN2B. It is a valuable research tool for studying NMDA receptor function in neurological disorders, utilized in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry

Images & Validation

Key Properties

CAS Number459836-30-7
MW454.21
Purity98.00% (May vary between batches)
FormulaC17H17BrN3O5P
SMILESC(N[C@@H](C)C1=CC=C(Br)C=C1)(P(=O)(O)O)C2=C3C(=CC=C2)NC(=O)C(=O)N3
TargetCaspase,NMDAR,iGluR,Apoptosis
SolubilityDMSO:6 mg/mL (13.21 mM)

Bioactivity

Target IC50
NMDAR:270 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PEAQX, Inhibitor, hNMDA 1A/2A receptors, iGluR, Ionotropic glutamate receptors, inhibit, NVP-AAM 077, NVP-AAM077, NVP-AAM-077

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

PEAQX (orb1303092)

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Step 1: Enter information below

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 70.00
2 mg
$ 80.00
5 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 140.00
10 mg
$ 170.00
25 mg
$ 270.00
50 mg
$ 400.00
100 mg
$ 540.00
200 mg
$ 760.00
DispatchUsually dispatched within 3-5 working days
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