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Pantoprazole-d8

SKU: orb3027457

Description

Pantoprazole-d8 (BY1023-d8) sodium is a deuterium-labeled version of Pantoprazole. Pantoprazole (BY1023) is an orally active, potent proton pump inhibitor (PPI). As a substituted benzimidazole, Pantoprazole effectively inhibits H+/K+-ATPase with an IC50 of 6.8 μM. It enhances pH stability and possesses antisecretory and anti-ulcer properties. When combined with Doxorubicin, Pantoprazole significantly extends tumor growth delay.

Research Area

Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW413.40
FormulaC16H6D8F2N3NaO4S
SMILESO=S(C1=NC2=CC(OC(F)F)=CC=C2[N-]1)C([2H])([2H])C3=C(C(OC([2H])([2H])[2H])=C([2H])C([2H])=N3)OC[2H].[Na+]
TargetApoptosis,Autophagy,Antibacterial,Proton pump

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Pantoprazole-d8 (orb3027457)

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