Palbociclib-propargyl

SKU: orb1987879

Description

CP-10 is a potent CDK6-targeting PROTAC composed of a palbociclib-based warhead linked to a CRBN ligand. It demonstrates high degradation potency with a DC50 of 2.1 nM, making it a valuable chemical probe for studying CDK6 biology in cancer research and for evaluating targeted protein degradation strategies in vitro.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2366269-23-8
• MW: 485.58
• Formula: C₂₇H₃₁N₇O₂
• SMILES: CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CC#C)CC3)nc2n(C2CCCC2)c1=O
• Target: Ligands for Target Protein for PROTAC,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139600348