Palbociclib-d8

SKU: orb1992735

Description

Palbociclib-d8 is a deuterated analog of Palbociclib, a potent and selective CDK4/6 inhibitor (IC50=11/16 nM). It is widely used as an internal standard in LC-MS for pharmacokinetic studies in breast cancer research, particularly for ER+/HER2- subtypes, both in vitro and in vivo.

Research Area

Cell Biology

Key Properties

• CAS Number: 1628752-83-9
• MW: 455.58
• Formula: C₂₄H₂₁D₈N₇O₂
• SMILES: O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4C(C(NC(C4([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])N2)C5CCCC5
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

76974685