Oxybuprocaine hydrochloride

SKU: orb1310670

Description

Oxybuprocaine hydrochloride is a local anesthetic agent extensively utilized in ophthalmological and otolaryngological procedures. Its application extends to research, where it serves as a sodium channel blocker in both in vitro electrophysiology studies and in vivo models for investigating topical anesthesia.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 5987-82-6
• MW: 344.88
• Purity: 99.87%
• Formula: C₁₇H₂₉ClN₂O₃
• SMILES: Cl.CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC
• Target: Sodium Channel
• Solubility: Ethanol:64 mg/mL (185.57 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.8 mM);DMSO:64 mg/mL (185.57 mM);H2O:63 mg/mL (182.67 mM)

Bioactivity

• In Vivo:
  Similar to bupivacaine or lidocaine, Oxybuprocaine produces dose-related spinal cord blockade of proprioception, locomotion, and injury perception.Oxybuprocaine binds to sodium channels and reversibly stabilizes neuronal cell membranes to make them less permeable to sodium ions.Oxybuprocaine inhibits the depolarization of neuronal cell membranes, thereby Oxybuprocaine inhibits the depolarization of neuronal cell membrane, thus blocking the initiation and conduction of nerve impulses.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

disease, cornea, conjunctiva, Benoxinate, ALO, impulses, inhibit, ophthalmology, nerve, Na+ channels, Na channels, Parkinson's, painful, Inhibitor, otolaryngology, Oxybuprocaine hydrochloride, Oxybuprocaine Hydrochloride, Oxybuprocaine, Oxybuprocaine HCl, propagation, Risedronic Acid, Risedronic Acid, SodiumChannel, Sodium Channel, sclera

Compound Identifiers

PubChem CID

6420040