Oxeladin citrate

SKU: orb1224804

Description

Oxeladin is a cough suppressant. It is a highly potent and effective drug used to treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is free of risk of dependence or addiction. Oxeladin has none of the side effects (such as hypnosis, respiratory depression, tolerance, constipation and analgesia) which are present when common antitussives, such as codeine and its derivatives, are used. It may be used at every age, as well as in patients with heart disease, since it has a high level of safety and a great selectivity to act on the bulbar centre of cough.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 52432-72-1
• MW: 527.6
• Purity: >98% (HPLC)
• Formula: C₂₆H₄₁NO₁₀
• SMILES: OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)CCOCCOC(=O)C(CC)(CC)C1=CC=CC=C1
• Target: Others
• Solubility: Soluble in DMSO

Bioactivity

• In Vivo:
  Animal model: Middle cerebral artery occlusion model rats. Dosage: 135 mg/kg/day. Administration: MCAO for 2 d, then Oral gavage (p.o.) for 11 d. Result: Significantly improved neurological function on days 3, 7, and 14 following MCAO, decreased final extent of infarct after 14 days. Increased the amount of mature brain-derived neurotrophic factor in the cerebral cortex 2, 6, and 24 h after single oral dose.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others