OTs-PEG3-NHCO-Thalidomide

SKU: orb2802161

Description

OTs-PEG3-NHCO-Thalidomide is a bifunctional linker utilized in constructing PROTAC molecules, such as degrader 6, which targets α-synuclein for ubiquitination and degradation. This compound is applied in biochemical research for studying Parkinson's disease mechanisms, supporting both in vitro and in vivo experimental models of neurodegeneration.

Research Area

Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2716123-18-9
• MW: 661.68
• Formula: C₃₀H₃₅N₃O₁₂S
• SMILES: O=C(NCCOCCOCCOCCOS(=O)(=O)C1=CC=C(C=C1)C)COC2=CC=CC=3C(=O)N(C(=O)C23)C4C(=O)NC(=O)CC4
• Target: Tie-2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156865614